Calpain 1, Large Subunit (CAPNL1) (N-Term) Peptide
CAPNL1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974442
Quick Overview for Calpain 1, Large Subunit (CAPNL1) (N-Term) Peptide (ABIN974442)
Target
CAPNL1
(Calpain 1, Large Subunit (CAPNL1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- EFWSALLEKA YAKVNGSYEA LSGGSTSEGF EDFTGGVTEW YELRKAPSDL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CAPN1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CAPNL1 (Calpain 1, Large Subunit (CAPNL1))
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Background
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The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: CANP, CANP1, CANPL1, muCANP, muCL
Protein Interaction Partner: ACTC1,ACTN2,CAPNS1,COL1A1,COL3A1,CREG1,CTSC,DES,ECHS1,FHL2,GPT,LAMTOR1,MYBPC3,NFE2L1,PRMT5,PTGDS,SH3BGR,SLIT3,SYNE1,TINAGL1,UFSP2,VIM,ACTC1,ACTN2,ARF6,BCL2L1,BID,CAPNS1,CASP14,CAST,CBL,CDK5R1,COL1A1,COL3A1,CREG1,CTSC,DES,ECHS1,F2R,F2RL1,FHL2,GNG12,GPT,GRI
Protein Size: 714 -
Molecular Weight
- 82 kDa
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Gene ID
- 823
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NCBI Accession
- NM_005186, NP_005177
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UniProt
- P07384
Target
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