Caspase Recruitment Domain Family, Member 17 (CARD17) (Middle Region) Peptide
CARD17
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974462
Quick Overview for Caspase Recruitment Domain Family, Member 17 (CARD17) (Middle Region) Peptide (ABIN974462)
Target
CARD17
(Caspase Recruitment Domain Family, Member 17 (CARD17))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Sequence
- MDKARALLDS VIRKGAPACQ ICITYICEED SHLAGTLGLS AGPTSGNHLT
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-CARD17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))
-
Background
-
As a regulator of procaspase-1/CASP1 activation, CARD17 is implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. CARD17 inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, CARD17 do not induce NF-kappa-B activation.
Alias Symbols: INCA
Protein Interaction Partner: CARD16,CARD17,CARD18,CASP1
Protein Size: 110 -
Molecular Weight
- 12 kDa
-
Gene ID
- 440068
-
NCBI Accession
- NM_001007232, NP_001007233
-
UniProt
- Q5XLA6
Target
-
You are here:
