Caspase Recruitment Domain Family, Member 17 (CARD17) (Middle Region) Peptide
CARD17
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CARD17 products
- CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MDKARALLDS VIRKGAPACQ ICITYICEED SHLAGTLGLS AGPTSGNHLT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CARD17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))
- Background
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As a regulator of procaspase-1/CASP1 activation, CARD17 is implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. CARD17 inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, CARD17 do not induce NF-kappa-B activation.
Alias Symbols: INCA
Protein Interaction Partner: CARD16,CARD17,CARD18,CASP1
Protein Size: 110 - Molecular Weight
- 12 kDa
- Gene ID
- 440068
- NCBI Accession
- NM_001007232, NP_001007233
- UniProt
- Q5XLA6
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