Caspase Recruitment Domain Family, Member 9 (CARD9) (Middle Region) Peptide
Quick Overview for Caspase Recruitment Domain Family, Member 9 (CARD9) (Middle Region) Peptide (ABIN974463)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- ALHQEQVLRN PHDAGLSSGE PPEKERRRLK ESFENYRRKR ALRKMQKGWR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CARD9 Antibody(ARP57704_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))
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Background
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The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.
Alias Symbols: hCARD9, CANDF2
Protein Interaction Partner: BCL10,CARD9,BCL10,CARD9,CCDC85B,KIAA0408,BCL10,CARD9,CCDC85B,KIAA0408
Protein Size: 536 -
Molecular Weight
- 62 kDa
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Gene ID
- 64170
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NCBI Accession
- NM_052813, NP_434700
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UniProt
- Q9H257
Target
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