Chromobox Homolog 1 (CBX1) Peptide
CBX1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974509
Quick Overview for Chromobox Homolog 1 (CBX1) Peptide (ABIN974509)
Target
CBX1
(Chromobox Homolog 1 (CBX1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CBX1 antibody (Catalog #: ARP34427_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CBX1 (Chromobox Homolog 1 (CBX1))
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Background
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CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.[supplied by OMIM].
Alias Symbols: CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta
Protein Interaction Partner: DNMT3B,MKI67,ARL5A,C11orf30,C1orf103,CBX1,CBX3,CBX5,CHAF1A,DNMT1,DNMT3A,DNMT3B,HIST1H1E,HIST1H3A,HIST1H3C,HIST3H3,PIM1,RPL12,SUV39H1,TRIM24,TRIM28,UCHL1,ARL5A,BAP1,C11orf30,C1orf103,CBX1,CBX3,CBX5,DNMT1,DNMT3A,MYOD1,PIM1,RB1,RPL12,SP100,SUV39H1,Suv39h1,TRIM28,UCHL1,USP17L2
Protein Size: 185 -
Molecular Weight
- 21 kDa
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Gene ID
- 10951
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NCBI Accession
- NM_006807, NP_006798
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UniProt
- P83916
Target
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