Coiled-Coil Domain Containing 50 (CCDC50) (Middle Region) Peptide
Quick Overview for Coiled-Coil Domain Containing 50 (CCDC50) (Middle Region) Peptide (ABIN974551)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- KAKEREKSSL DKRKQDPEWK PKTAKAANSK SKESDEPHHS KNERPARPPP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CCDC50 Antibody(ARP53356_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))
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Background
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CCDC50 is a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling.
Alias Symbols: C3orf6, DFNA44, YMER
Protein Interaction Partner: RPS3A,EGFR,UBC
Protein Size: 482 -
Molecular Weight
- 56 kDa
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Gene ID
- 152137
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NCBI Accession
- NM_178335, NP_848018
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UniProt
- Q8IVM0
Target
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