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Chaperonin Containing TCP1, Subunit 3 (Gamma) (CCT3) (C-Term) Peptide

CCT3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN974634
  • Target See all CCT3 products
    CCT3 (Chaperonin Containing TCP1, Subunit 3 (Gamma) (CCT3))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    KELGIWEPLA VKLQTYKTAV ETAVLLLRID DIVSGHKKKG DDQSRQGGAP
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CCT3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CCT3 (Chaperonin Containing TCP1, Subunit 3 (Gamma) (CCT3))
    Background
    The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8.

    Alias Symbols: CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5

    Protein Interaction Partner: RAF1,RAF1,EIF2B2,HNRNPA0,HSPA8,PAFAH1B2,RAF1,SSSCA1,VHL,XRCC6,ATG16L1,CDK9,CTTNBP2,EIF2B2,FANCA,IGBP1,MAPK6,MOB4,PAFAH1B2,PPP2CA,PPP2CB,PPP2R2C,PPP4C,RAF1,RFWD2,SSSCA1,STK24,STRN,STRN3,TCP1,VHL,WDR82

    Protein Size: 545
    Molecular Weight
    60 kDa
    Gene ID
    7203
    NCBI Accession
    NM_005998, NP_005989
    UniProt
    P49368
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