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Chaperonin Containing TCP1, Subunit 3 (Gamma) (CCT3) (C-Term) Peptide

CCT3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN974634

Quick Overview for Chaperonin Containing TCP1, Subunit 3 (Gamma) (CCT3) (C-Term) Peptide (ABIN974634)

Target

CCT3 (Chaperonin Containing TCP1, Subunit 3 (Gamma) (CCT3))

Origin

Human

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    KELGIWEPLA VKLQTYKTAV ETAVLLLRID DIVSGHKKKG DDQSRQGGAP

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-CCT3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CCT3 (Chaperonin Containing TCP1, Subunit 3 (Gamma) (CCT3))

    Background

    The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8.

    Alias Symbols: CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5

    Protein Interaction Partner: RAF1,RAF1,EIF2B2,HNRNPA0,HSPA8,PAFAH1B2,RAF1,SSSCA1,VHL,XRCC6,ATG16L1,CDK9,CTTNBP2,EIF2B2,FANCA,IGBP1,MAPK6,MOB4,PAFAH1B2,PPP2CA,PPP2CB,PPP2R2C,PPP4C,RAF1,RFWD2,SSSCA1,STK24,STRN,STRN3,TCP1,VHL,WDR82

    Protein Size: 545

    Molecular Weight

    60 kDa

    Gene ID

    7203

    NCBI Accession

    NM_005998, NP_005989

    UniProt

    P49368
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