Natural Killer Cell Receptor 2B4 (CD244) (C-Term) Peptide
Quick Overview for Natural Killer Cell Receptor 2B4 (CD244) (C-Term) Peptide (ABIN974659)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- FRFWPFLVII VILSALFLGT LACFCVWRRK RKEKQSETSP KEFLTIYEDV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CD244 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
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Background
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This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: 2B4, NAIL, NKR2B4, Nmrk, SLAMF4
Protein Interaction Partner: SH2D1A,ARHGEF7,CD247,CD48,LAT,SH2D1B,SH2D1A
Protein Size: 365 -
Molecular Weight
- 40 kDa
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Gene ID
- 51744
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NCBI Accession
- NM_016382, NP_057466
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UniProt
- B2R820
Target
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