CD8a Molecule (CD8A) (Middle Region) Peptide
CD8A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974700
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for CD8a Molecule (CD8A) (Middle Region) Peptide (ABIN974700)
Target
CD8 alpha (CD8A)
(CD8a Molecule (CD8A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- RGAAASPTFL LYLSQNKPKA AEGLDTQRFS GKRLGDTFVL TLSDFRRENE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CD8A Antibody(ARP59113_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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Background
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The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD8, Leu2, MAL, p32
Protein Interaction Partner: B2M,CD3D,CD8A,CD8B,HLA-A,HLA-B,HLA-C,HLA-E,HLA-G,LAT,LCK,LGALS1,PTPRC,SREK1,SRSF1,CD3D,CD59,CD8A,CD8B,HLA-A,HLA-B,HLA-C,HLA-G,PTPRC
Protein Size: 235 -
Molecular Weight
- 24 kDa
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Gene ID
- 925
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NCBI Accession
- NM_001145873, NP_001139345
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UniProt
- P01732
Target
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