CDC42 Effector Protein (Rho GTPase Binding) 4 (CDC42EP4) (N-Term) Peptide
CDC42EP4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974734
$160.46
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100 μg
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Quick Overview for CDC42 Effector Protein (Rho GTPase Binding) 4 (CDC42EP4) (N-Term) Peptide (ABIN974734)
Target
CDC42EP4
(CDC42 Effector Protein (Rho GTPase Binding) 4 (CDC42EP4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CDC42EP4 antibody (Catalog #: ARP54839_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CDC42EP4 (CDC42 Effector Protein (Rho GTPase Binding) 4 (CDC42EP4))
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Background
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CDC42EP4 is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. The protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, the protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.
Alias Symbols: BORG4, CEP4, KAIA1777, MGC17125, MGC3740
Protein Interaction Partner: RHOQ,TGFBR1,WDR6,POLR3H,WDR6
Protein Size: 356 -
Molecular Weight
- 38 kDa
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Gene ID
- 23580
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NCBI Accession
- NM_012121, NP_036253
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UniProt
- Q9H3Q1
Target
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