Cyclin-Dependent Kinase Inhibitor 3 (CDKN3) Peptide
CDKN3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974789
Quick Overview for Cyclin-Dependent Kinase Inhibitor 3 (CDKN3) Peptide (ABIN974789)
Target
CDKN3
(Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CDKN3 antibody (Catalog #: ARP53629_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))
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Background
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CDKN3 belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CDI1, CIP2, FLJ25787, KAP, KAP1, MGC70625
Protein Interaction Partner: CDC25A,CDK1,CDK2,CDK3,CDKN3,CEBPA,MS4A3,CDK1,CDK2,MS4A3
Protein Size: 212 -
Molecular Weight
- 23 kDa
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Gene ID
- 1033
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NCBI Accession
- NM_005192, NP_005183
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UniProt
- Q16667
Target
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