Chromatin Licensing and DNA Replication Factor 1 (CDT1) Peptide
CDT1
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN974796
Quick Overview for Chromatin Licensing and DNA Replication Factor 1 (CDT1) Peptide (ABIN974796)
Target
CDT1
(Chromatin Licensing and DNA Replication Factor 1 (CDT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CDT1 antibody (Catalog #: ARP46350_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))
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Background
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CDT1 cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. It binds DNA in a sequence-, strand-, and conformation-independent manner and is a potential oncogene.
Alias Symbols: DUP, RIS2
Protein Interaction Partner: DDB1,CCNA2,CDC5L,CDC6,CDK1,CDK2,CDT1,GMNN,MCM6,ORC1L,ORC2L,PCNA,SKP2,UBB,ANAPC5,ANAPC7,BAZ1B,CDC20,CDC23,CDC6,CUL1,E2F1,FZR1,GMNN,GRWD1,KPNA2,KPNB1,MCM4,MCM6,MCM7,NPM1,PCNA,SKP2,SMARCA5,TOP1,TOP2A
Protein Size: 546 -
Molecular Weight
- 60 kDa
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Gene ID
- 81620
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NCBI Accession
- NM_030928, NP_112190
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UniProt
- Q9H211
Target
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