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Chromodomain Protein, Y-Like (CDYL) (N-Term) Peptide

CDYL Reactivity: Human Host: Synthetic BP, WB, ICC
Catalog No. ABIN974805

Quick Overview for Chromodomain Protein, Y-Like (CDYL) (N-Term) Peptide (ABIN974805)

Target

CDYL (Chromodomain Protein, Y-Like (CDYL))

Origin

Human

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunocytochemistry (ICC)
  • Protein Region

    N-Term

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-CDYL antibody (Catalog #: ARP49096_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CDYL (Chromodomain Protein, Y-Like (CDYL))

    Background

    CDYL acts as repressor of transcription. CDYL has histone acetyltransferase activity, with a preference for histone H4.Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.

    Alias Symbols: CDYL1, DKFZP586C1622, MGC131936

    Protein Interaction Partner: HDAC1,HDAC2,HTRA1,HDAC1,HDAC2

    Protein Size: 544

    Molecular Weight

    60 kDa

    Gene ID

    9425

    NCBI Accession

    NM_004824, NP_004815

    UniProt

    Q9Y232
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