Chromodomain Protein, Y-Like (CDYL) (N-Term) Peptide
Quick Overview for Chromodomain Protein, Y-Like (CDYL) (N-Term) Peptide (ABIN974805)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CDYL antibody (Catalog #: ARP49096_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CDYL (Chromodomain Protein, Y-Like (CDYL))
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Background
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CDYL acts as repressor of transcription. CDYL has histone acetyltransferase activity, with a preference for histone H4.Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.
Alias Symbols: CDYL1, DKFZP586C1622, MGC131936
Protein Interaction Partner: HDAC1,HDAC2,HTRA1,HDAC1,HDAC2
Protein Size: 544 -
Molecular Weight
- 60 kDa
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Gene ID
- 9425
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NCBI Accession
- NM_004824, NP_004815
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UniProt
- Q9Y232
Target
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