Centromere Protein H (CENPH) (N-Term) Peptide
CENPH
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974835
Quick Overview for Centromere Protein H (CENPH) (N-Term) Peptide (ABIN974835)
Target
CENPH
(Centromere Protein H (CENPH))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MEEQPQMQDA DEPADSGGEG RAGGPPQVAG AQAACSEDRM TLLLRLRAQT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CENPH Antibody(ARP58265_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CENPH (Centromere Protein H (CENPH))
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Background
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Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
Alias Symbols: NNF1, PMF1
Protein Interaction Partner: CENPH,KIF2C,CENPH,KIF2C,PMVK
Protein Size: 247 -
Molecular Weight
- 27 kDa
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Gene ID
- 64946
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NCBI Accession
- NM_022909, NP_075060
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UniProt
- Q9H3R5
Target
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