Carboxylesterase 3 (CES3) (Middle Region) Peptide
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- Target See all CES3 products
- CES3 (Carboxylesterase 3 (CES3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TPGIIDSHPW PLAQKIANTL ACSSSSPAEM VQCLQQKEGE ELVLSKKLKN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CES3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CES3 (Carboxylesterase 3 (CES3))
- Background
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This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.
Alias Symbols: ES31, FLJ21736
Protein Interaction Partner: BMPR2
Protein Size: 571 - Molecular Weight
- 59 kDa
- Gene ID
- 23491
- NCBI Accession
- NM_024922, NP_079198
- UniProt
- Q6UWW8
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