Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (N-Term) Peptide
CHAF1B
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974888
Quick Overview for Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (N-Term) Peptide (ABIN974888)
Target
CHAF1B
(Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-CHAF1B antibody (Catalog #: ARP45826_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))
-
Background
-
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. CHAF1B corresponds to the p60 subunit and is required for chromatin assembly after replication. CHAF1B is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CAF-1, CAF-IP60, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7
Protein Interaction Partner: HIST1H3E,ASF1A,ASF1B,CDK1,CDK2,CHAF1A,HIST1H3B,RBBP4,ASF1A,ASF1B,BAZ1B,CBX5,CHAF1A
Protein Size: 559 -
Molecular Weight
- 61 kDa
-
Gene ID
- 8208
-
NCBI Accession
- NM_005441, NP_005432
-
UniProt
- Q13112
Target
-
You are here:
