Charged Multivesicular Body Protein 1B (CHMP1B) (N-Term) Peptide
CHMP1B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CHMP1B products
- CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KIKKAIQKGN MEVARIHAEN AIRQKNQAVN FLRMSARVDA VAARVQTAVT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CHMP1B Antibody(ARP57408_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))
- Background
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CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Alias Symbols: C10orf2, C18-ORF2, C18orf2, CHMP1.5, Vps46-2, Vps46B, hVps46-2
Protein Interaction Partner: C15orf23,CHMP1A,CHMP1B,CHMP4B,CHMP5,CNOT10,RAB11A,RASSF7,SNRNP200,SSRP1,STAMBP,SUCLG1,VPS4A,VPS4B,STAMBP,USP8
Protein Size: 199 - Molecular Weight
- 22 kDa
- Gene ID
- 57132
- NCBI Accession
- NM_020412, NP_065145
- UniProt
- Q7LBR1
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