Charged Multivesicular Body Protein 1B (CHMP1B) (N-Term) Peptide
CHMP1B
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974925
Quick Overview for Charged Multivesicular Body Protein 1B (CHMP1B) (N-Term) Peptide (ABIN974925)
Target
CHMP1B
(Charged Multivesicular Body Protein 1B (CHMP1B))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- KIKKAIQKGN MEVARIHAEN AIRQKNQAVN FLRMSARVDA VAARVQTAVT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CHMP1B Antibody(ARP57408_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))
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Background
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CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Alias Symbols: C10orf2, C18-ORF2, C18orf2, CHMP1.5, Vps46-2, Vps46B, hVps46-2
Protein Interaction Partner: C15orf23,CHMP1A,CHMP1B,CHMP4B,CHMP5,CNOT10,RAB11A,RASSF7,SNRNP200,SSRP1,STAMBP,SUCLG1,VPS4A,VPS4B,STAMBP,USP8
Protein Size: 199 -
Molecular Weight
- 22 kDa
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Gene ID
- 57132
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NCBI Accession
- NM_020412, NP_065145
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UniProt
- Q7LBR1
Target
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