Chloride Channel Kb (CLCNKB) Peptide
CLCNKB
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CLCNKB products
- CLCNKB (Chloride Channel Kb (CLCNKB))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CLCNKB antibody (Catalog #: ARP34916_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CLCNKB (Chloride Channel Kb (CLCNKB))
- Background
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Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94 % sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.
Alias Symbols: RP11-5P18.8, CLCKB, ClC-K2, MGC24087, hClC-Kb, ClC-Kb
Protein Size: 462 - Molecular Weight
- 50 kDa
- Gene ID
- 1188
- NCBI Accession
- NM_000085
- UniProt
- Q8WW53
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