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Chloride Channel Kb (CLCNKB) Peptide

CLCNKB Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975026

Quick Overview for Chloride Channel Kb (CLCNKB) Peptide (ABIN975026)

Target

CLCNKB (Chloride Channel Kb (CLCNKB))

Origin

Human

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-CLCNKB antibody (Catalog #: ARP34916_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CLCNKB (Chloride Channel Kb (CLCNKB))

    Background

    Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94 % sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.

    Alias Symbols: RP11-5P18.8, CLCKB, ClC-K2, MGC24087, hClC-Kb, ClC-Kb

    Protein Size: 462

    Molecular Weight

    50 kDa

    Gene ID

    1188

    NCBI Accession

    NM_000085

    UniProt

    Q8WW53
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