Chloride Channel Kb (CLCNKB) Peptide
CLCNKB
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN975027
Quick Overview for Chloride Channel Kb (CLCNKB) Peptide (ABIN975027)
Target
CLCNKB
(Chloride Channel Kb (CLCNKB))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CLCNKB antibody (Catalog #: ARP34917_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CLCNKB (Chloride Channel Kb (CLCNKB))
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Background
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Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94 % sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.
Alias Symbols: CLCKB, ClC-K2, ClC-Kb, hClC-Kb
Protein Size: 687 -
Molecular Weight
- 76 kDa
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Gene ID
- 1188
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NCBI Accession
- NM_000085, NP_000076
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UniProt
- P51801
Target
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