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Cannabinoid Receptor 2 (CNR2) (C-Term) Peptide

CNR2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975138

Quick Overview for Cannabinoid Receptor 2 (CNR2) (C-Term) Peptide (ABIN975138)

Target

CNR2 (Cannabinoid Receptor 2 (CNR2))

Origin

Human

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    MVNPVIYALR SGEIRSSAHH CLAHWKKCVR GLGSEAKEEA PRSSVTETEA

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-CNR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CNR2 (Cannabinoid Receptor 2 (CNR2))

    Background

    The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.

    Alias Symbols: CB2, CX5

    Protein Interaction Partner: GNA15

    Protein Size: 360

    Molecular Weight

    40 kDa

    Gene ID

    1269

    NCBI Accession

    NM_001841, NP_001832

    UniProt

    P34972
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