Coilin (COIL) Peptide
COIL
Reactivity: Human
Host: Synthetic
BP, WB
-
- Target See all Coilin (COIL) products
- Coilin (COIL)
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-COIL antibody (Catalog #: ARP53621_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- Coilin (COIL)
- Background
-
COIL is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies.The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CLN80, p80-coilin
Protein Interaction Partner: ANKS1B,ANKS1B,ACTN1,ACTN2,ACTN4,ATXN1,BYSL,C1QBP,CCDC136,CCNE1,CDK2,CEP70,CEP76,COIL,CSNK2B,CYB5R2,DHX16,DNAJA3,FAM115A,FHL5,FXR2,GCC1,KALRN,KAZ,KLC2,KLC4,KLHDC5,KLHL8,KPNA3,LNX1,MAD1L1,MYO5B,NIF3L1,NOLC1,NUDT18,PIAS4,PICK1,PLEKHG4,PREPL,PRMT1,PRMT8,PSMA1,PSME3,SART3,SCYL1,SMN2,SNRPB,SNX6,TAF9,TCEB3B,TFCP2,TGS1,TSPYL2,WDYHV1,ZBTB25,ZNF277,ATXN1,CCNE1,COIL,NOLC1,SMN1,SNRPB
Protein Size: 576 - Molecular Weight
- 63 kDa
- Gene ID
- 8161
- NCBI Accession
- NM_004645, NP_004636
- UniProt
- P38432
-
You are here:
