COP9 Signalosome Subunit 4 (COPS4) (Middle Region) Peptide
COPS4
Reactivity: Human, Drosophila melanogaster
Host: Synthetic
BP, WB
Catalog No. ABIN975193
Quick Overview for COP9 Signalosome Subunit 4 (COPS4) (Middle Region) Peptide (ABIN975193)
Target
COPS4
(COP9 Signalosome Subunit 4 (COPS4))
Origin
Human, Drosophila melanogaster
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-COPS4 antibody (Catalog #: ARP56841_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- COPS4 (COP9 Signalosome Subunit 4 (COPS4))
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Background
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COPS4 is one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases.This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC10899, MGC15160, CSN4
Protein Interaction Partner: COPS2,COPS3,COPS4,COPS6,COPS7A,COPS8,GPS1,C19orf57,CCDC85B,COPS2,COPS3,COPS4,COPS5,COPS6,COPS7A,COPS8,CUL5,MBIP,RCBTB2,TP53,USHBP1,BTRC,C19orf57,CCDC85B,COPS5,COPS6,COPS8,CUL4A,DDB1,KLHL13,MBIP,RCBTB2,USHBP1,WDR8
Protein Size: 406 -
Molecular Weight
- 46 kDa
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Gene ID
- 51138
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NCBI Accession
- NM_016129, NP_057213
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UniProt
- Q9BT78
Target
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