Cytochrome C Oxidase Subunit 3 (COX-3) Peptide
Quick Overview for Cytochrome C Oxidase Subunit 3 (COX-3) Peptide (ABIN975219)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-COX3 antibody (Catalog #: ARP50251_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- COX3 (COX-3) (Cytochrome C Oxidase Subunit 3 (COX-3))
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Background
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COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
Alias Symbols: MTCO3, COIII
Protein Interaction Partner: SNCA
Protein Size: 260 -
Molecular Weight
- 29 kDa
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Gene ID
- 4514
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NCBI Accession
- NP_536849
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UniProt
- P00414
Target
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