Cleavage and Polyadenylation Specific Factor 1, 160kDa (CPSF1) Peptide
CPSF1
Reactivity: Human
Host: Synthetic
BP, WB
Quick Overview for Cleavage and Polyadenylation Specific Factor 1, 160kDa (CPSF1) Peptide (ABIN975261)
Target
CPSF1
(Cleavage and Polyadenylation Specific Factor 1, 160kDa (CPSF1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CPSF1 antibody (Catalog #: ARP40741_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CPSF1 (Cleavage and Polyadenylation Specific Factor 1, 160kDa (CPSF1))
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Background
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CPSF1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.
Alias Symbols: CPSF160, HSU37012, P/cl.18
Protein Interaction Partner: BAT2,CPSF1,MCM2,POLR2A,TAF11,TAF12,TAF13,TAF5,TAF7,BAT2,COPS2,COPS5,CSN1S1,CSTF2
Protein Size: 1443 -
Molecular Weight
- 161 kDa
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Gene ID
- 29894
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NCBI Accession
- NM_013291, NP_037423
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UniProt
- Q10570
Target
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