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Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2) Peptide

CPSF2 Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN975262

Quick Overview for Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2) Peptide (ABIN975262)

Target

CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Characteristics

This is a synthetic peptide designed for use in combination with anti-CPSF2 antibody (Catalog #: ARP40857_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2) peptide
CPSF2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

Background

CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. It belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily.

Alias Symbols: CPSF100, KIAA1367

Protein Interaction Partner: POLR2A,CSTF2,RNPS1

Protein Size: 782

Molecular Weight

88 kDa

Gene ID

53981

NCBI Accession

NM_017437, NP_059133

UniProt

Q9P2I0

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