Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (Middle Region) Peptide
CPT1A
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN975267
Quick Overview for Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) (Middle Region) Peptide (ABIN975267)
Target
CPT1A
(Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CPT1A antibody (Catalog #: ARP44796_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Carnitine Palmitoyltransferase 1A (Liver) (CPT1A) peptide
CPT1A Reactivity: Mouse, Pig, Rat Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
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Background
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The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CPT1, CPT1-L, L-CPT1
Protein Interaction Partner: BCL2
Protein Size: 756 -
Molecular Weight
- 86 kDa
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Gene ID
- 1374
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NCBI Accession
- NM_001031847, NP_001027017
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UniProt
- P50416
Target
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