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CAMP Responsive Element Binding Protein 3 (CREB3) (Middle Region) Peptide

CREB3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975283

Quick Overview for CAMP Responsive Element Binding Protein 3 (CREB3) (Middle Region) Peptide (ABIN975283)

Target

CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Origin

Human

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-CREB3 antibody (Catalog #: ARP32768_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

    Background

    CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined.This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: LUMAN, LZIP, MGC15333, MGC19782

    Protein Interaction Partner: APPBP2,BNIP2,CCR1,EMD,HCFC1,MALL,NFIL3,STX8,APPBP2,BNIP2,EMD,HCFC1,MALL,STX8

    Protein Size: 371

    Molecular Weight

    41 kDa

    Gene ID

    10488

    NCBI Accession

    NM_006368, NP_006359

    UniProt

    O43889
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