Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Peptide
KCNIP3
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN975353
Quick Overview for Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Peptide (ABIN975353)
Target
DREAM (KCNIP3)
(Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-CSEN antibody (Catalog #: ARP31932_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
-
Background
-
CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
Alias Symbols: CSEN, DREAM, KCHIP3
Protein Interaction Partner: CASP3,CD177,CREB1,CREM,PSEN1,PSEN2,CD177,CREB1,CREM,CRK,PSEN1,PSEN2
Protein Size: 256 -
Molecular Weight
- 29 kDa
-
Gene ID
- 30818
-
NCBI Accession
- NM_013434, NP_038462
-
UniProt
- Q9Y2W7
Target
-
You are here:
