Cathepsin E (CTSE) (C-Term) Peptide
CTSE
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Cathepsin E (CTSE) products
- Cathepsin E (CTSE)
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GILGLGYPSL AVGGVTPVFD NMMAQNLVDL PMFSVYMSSN PEGGAGSELI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CTSE Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Cathepsin E (CTSE)
- Background
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The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.
Alias Symbols: CATE
Protein Size: 363 - Molecular Weight
- 40 kDa
- Gene ID
- 1510
- NCBI Accession
- NM_148964, NP_683865
- UniProt
- P14091
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