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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 50 (DDX50) Peptide

DDX50 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975669
  • Target See all DDX50 products
    DDX50 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 50 (DDX50))
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-DDX50 antibody (Catalog #: ARP36497_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DDX50 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 50 (DDX50))
    Background
    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX50 is a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. DDX50 and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. DDX50 gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined.

    Alias Symbols: GU2, GUB, RH-II/GuB

    Protein Size: 737
    Molecular Weight
    81 kDa
    Gene ID
    79009
    NCBI Accession
    NM_024045, NP_076950
    UniProt
    Q9BQ39
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