DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) Peptide
DDX21
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975676
Quick Overview for DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) Peptide (ABIN975676)
Target
DDX21
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DDX21 antibody (Catalog #: ARP36374_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
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Background
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
Alias Symbols: GUA, GURDB, RH-II/GU, RH-II/GuA
Protein Interaction Partner: JUN,PIAS1,JUN,LYAR,PSTPIP1,RRP1B,RTCD1,Rrp1b,SMNDC1
Protein Size: 783 -
Molecular Weight
- 86 kDa
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Gene ID
- 9188
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NCBI Accession
- NM_004728, NP_004719
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UniProt
- Q9NR30
Target
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