DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23) Peptide
DDX23
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975678
Quick Overview for DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23) Peptide (ABIN975678)
Target
DDX23
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DDX23 antibody (Catalog #: ARP36376_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DDX23 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23))
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Background
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DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex, it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.
Alias Symbols: prp28, PRPF28, U5-100K, U5-100KD
Protein Interaction Partner: CD2BP2,MEPCE,OTUB1,PRPF4,RNPS1,USP39
Protein Size: 820 -
Molecular Weight
- 90 kDa
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Gene ID
- 9416
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NCBI Accession
- NM_004818, NP_004809
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UniProt
- Q9BUQ8
Target
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