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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23) (C-Term) Peptide

DDX23 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975679

Quick Overview for DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23) (C-Term) Peptide (ABIN975679)

Target

DDX23 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23))

Origin

Human

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    GFDPPIIIFV NQKKGCDVLA KSLEKMGYNA CTLHGGKGQE QREFALSNLK

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-DDX23 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    DDX23 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23))

    Background

    This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex, it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing.

    Alias Symbols: MGC8416, PRPF28, U5-100K, U5-100KD, prp28

    Protein Interaction Partner: CD2BP2,MEPCE,OTUB1,PRPF4,RNPS1,TP63,TP73,USP39,WBP4

    Protein Size: 820

    Molecular Weight

    95 kDa

    Gene ID

    9416

    NCBI Accession

    NM_004818, NP_004809

    UniProt

    Q9BUQ8
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