DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) Peptide
DDX5
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975701
Quick Overview for DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5) Peptide (ABIN975701)
Target
DDX5
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DDX5 antibody (Catalog #: ARP36365_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
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Background
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX5 encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. DDX5 consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified.
Alias Symbols: p68, HLR1, G17P1, HUMP68
Protein Interaction Partner: CDKN1A,DDX17,ESR1,TP53,AKAP8,CALM1,CREBBP,DDX17,ESR1,FBL,NCOA1,NCOA2,NCOA3,NDRG1,PRKCA,SMAD3,TP53,AIRE,AKAP8,CDK9,CREBBP,DDX17,EP300,ESR1,ESR2,FBL,HDAC1,HNRNPA1,HNRNPH1,IPO11,KHDRBS2,MEPCE,NCOA1,NCOA2,NCOA3,OTUB1,SRA1,STK24,TCEA1
Protein Size: 614 -
Molecular Weight
- 68 kDa
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Gene ID
- 1655
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NCBI Accession
- NM_004396, NP_004387
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UniProt
- P17844
Target
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