2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2) (C-Term) Peptide
Quick Overview for 2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2) (C-Term) Peptide (ABIN975716)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- PIPRLGTKTE IAHSVLYLAS PLASYVSGIV LVVDGGSWMT FPNGIKQLLE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Decr2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))
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Background
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Decr2 is the auxiliary enzyme of beta-oxidation. Decr2 participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Decr2 catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Decr2 has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
Alias Symbols: -
Protein Size: 292 -
Molecular Weight
- 31 kDa
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Gene ID
- 26378
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NCBI Accession
- NM_011933, NP_036063
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UniProt
- Q9WV68
Target
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