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Dihydroorotate Dehydrogenase (DHODH) Peptide

DHODH Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975758

Quick Overview for Dihydroorotate Dehydrogenase (DHODH) Peptide (ABIN975758)

Target

DHODH (Dihydroorotate Dehydrogenase (DHODH))

Origin

Human

Source

  • 10
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-DHODH antibody (Catalog #: ARP41876_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    DHODH (Dihydroorotate Dehydrogenase (DHODH))

    Background

    DHODH catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: DHOdehase, URA1, POADS

    Protein Size: 395

    Molecular Weight

    43 kDa

    Gene ID

    1723

    NCBI Accession

    NM_001361, NP_001352

    UniProt

    Q02127
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