ATP-Dependent RNA Helicase A (DHX9) Peptide
DHX9
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN975790
Quick Overview for ATP-Dependent RNA Helicase A (DHX9) Peptide (ABIN975790)
Target
DHX9
(ATP-Dependent RNA Helicase A (DHX9))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DHX9 antibody (Catalog #: ARP36343_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DHX9 (ATP-Dependent RNA Helicase A (DHX9))
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Background
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DHX9 is a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as those that occur during transcription, and may play a role in X-linked gene expression.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as those that occur during transcription, and may play a role in X-linked gene expression. It contains 2 copies of a double-stranded RNA-binding domain, a DEXH core domain and an RGG box. The RNA-binding domains and RGG box influence and regulate RNA helicase activity.
Alias Symbols: DDX9, LKP, NDH II, NDHII, RHA, NDH2
Protein Interaction Partner: AKAP8L,BRCA1,DDX20,DHX9,GEMIN4,GTF2B,HDLBP,ILF3,JUN,KHDRBS1,MBD2,MGEA5,NXF1,PCNA,POLR2A,PRMT1,PRPF8,RELA,SIP1,SMN2,SMN2,SNRPB,SNRPB2,SRPK1,SSRP1,STAU1,TBP,TOP2A,AKAP8L,ARHGDIA,BRCA1,CNBP,DDX20,GEMIN4,GTF2B,HDLBP,HINFP,JUN,KHDRBS1,LYAR,MBD2,MEPCE,NXF1,PRMT1,RELA,SIP1,SMN1,TBP,TOP2A,XRCC5,XRCC6
Protein Size: 1279 -
Molecular Weight
- 141 kDa
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Gene ID
- 1660
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NCBI Accession
- NM_001357, NP_001348
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UniProt
- Q08211
Target
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