Diaphanous Homolog 1 (DIAPH1) (C-Term) Peptide
DIAPH1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975792
Quick Overview for Diaphanous Homolog 1 (DIAPH1) (C-Term) Peptide (ABIN975792)
Target
DIAPH1
(Diaphanous Homolog 1 (DIAPH1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- TGVMDSLLEA LQSGAAFRRK RGPRQANRKA GCAVTSLLAS ELTKDDAMAA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DIAPH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DIAPH1 (Diaphanous Homolog 1 (DIAPH1))
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Background
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This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: DFNA1, DIA1, DRF1, FLJ25265, LFHL1, hDIA1
Protein Interaction Partner: CENPA,PKD2,BAIAP2,CDC7,CENPA,PAX6,PKD2,PRPF40A,RAC1,RHOA,RHOC,XPO6,APBB1,GAS7,NEDD4,PRPF40A,RHOA,SRGAP2,TCERG1,UBC,WBP4,XPO6
Protein Size: 1272 -
Molecular Weight
- 141 kDa
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Gene ID
- 1729
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NCBI Accession
- NM_005219, NP_005210
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UniProt
- O60610
Target
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