Exosome Complex Exonuclease RRP44 (DIS3) Peptide
DIS3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DIS3 products
- DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DIS3 antibody (Catalog #: ARP40793_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
- Background
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DIS3, belonging to the ribonuclease II (RNB) family, has a 3'-5' exonuclease activity. It is a catalytic component of the exosome 3'->5' exoribonuclease complex required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and for mRNA decay. The protein is implicated in mitotic control and essential for cell division and spore germination. It may be involved in regulating protein dephosphorylation during mitosis.
Alias Symbols: DKFZp667L1817, FLJ10484, KIAA1008, MGC33035, RP11-342J4.3, RRP44, bA555G22.1, dis3p, EXOSC11
Protein Interaction Partner: EXOSC10,EXOSC2,EXOSC4,EXOSC5,EXOSC6,EXOSC7,EXOSC8,EXOSC9,MPP6,SKIV2L2,ZBTB17,C19orf62,ZBTB17
Protein Size: 958 - Molecular Weight
- 109 kDa
- Gene ID
- 22894
- NCBI Accession
- NM_014953, NP_055768
- UniProt
- Q9Y2L1
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