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Dickkopf Homolog 1 (DKK1) Peptide

DKK1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975815

Quick Overview for Dickkopf Homolog 1 (DKK1) Peptide (ABIN975815)

Target

DKK1 (Dickkopf Homolog 1 (DKK1))

Origin

Human

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-DKK1 antibody (Catalog #: ARP48015_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    DKK1 (Dickkopf Homolog 1 (DKK1))

    Background

    DKK1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

    Alias Symbols: DKK-1, SK

    Protein Interaction Partner: CTNNB1,KREMEN1,LRP5,LRP6,MDFI,SMAD9,CORO1A,LRP6,MDFI

    Protein Size: 266

    Molecular Weight

    26 kDa

    Gene ID

    22943

    NCBI Accession

    NM_012242, NP_036374

    UniProt

    O94907
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