Dickkopf Homolog 1 (DKK1) Peptide
DKK1
Reactivity: Human
Host: Synthetic
BP, WB
Quick Overview for Dickkopf Homolog 1 (DKK1) Peptide (ABIN975815)
Target
DKK1
(Dickkopf Homolog 1 (DKK1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DKK1 antibody (Catalog #: ARP48015_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Dickkopf Homolog 1 (DKK1) peptide
DKK1 Reactivity: Human, Cow, Dog, Pig, Rat Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DKK1 (Dickkopf Homolog 1 (DKK1))
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Background
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DKK1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Alias Symbols: DKK-1, SK
Protein Interaction Partner: CTNNB1,KREMEN1,LRP5,LRP6,MDFI,SMAD9,CORO1A,LRP6,MDFI
Protein Size: 266 -
Molecular Weight
- 26 kDa
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Gene ID
- 22943
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NCBI Accession
- NM_012242, NP_036374
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UniProt
- O94907
Target
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