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Dickkopf Homolog 1 (DKK1) (C-Term) Peptide

DKK1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN2183314
  • Target See all DKK1 products
    DKK1 (Dickkopf Homolog 1 (DKK1))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    CARHFWSKIC KPVLKEGQVC TKHRRKGSHG LEIFQRCYCG EGLSCRIQKD
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-DKK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DKK1 (Dickkopf Homolog 1 (DKK1))
    Synonyms
    DKK-1 Peptide, SK Peptide, AI414495 Peptide, SGY Peptide, SGY-1 Peptide, SGY1 Peptide, Soggy Peptide, mSgy Peptide, dkk1 Peptide, dkk Peptide, dkk-1 Peptide, xdkk1 Peptide, Xdkk-1 Peptide, Dickkopf1 Peptide, dickkopf-1 Peptide, mdkk-1 Peptide, dkk1-A Peptide, dickkopf WNT signaling pathway inhibitor 1 Peptide, dickkopf like acrosomal protein 1 Peptide, dickkopf-related protein 1 Peptide, dickkopf-like 1 Peptide, dickkopf WNT signaling pathway inhibitor 1b Peptide, dickkopf protein Peptide, dickkopf WNT signaling pathway inhibitor 1 S homeolog Peptide, DKK1 Peptide, Dkk1 Peptide, DKKL1 Peptide, LOC100228789 Peptide, Dkkl1 Peptide, dkk1b Peptide, dkk1 Peptide, dickkopf Peptide, dkk1.S Peptide
    Background
    DKK1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

    Alias Symbols: DKK-1, SK

    Protein Size: 266
    Molecular Weight
    29 kDa
    Gene ID
    22943
    NCBI Accession
    NM_012242, NP_036374
    UniProt
    O94907
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