Dihydrolipoyl Transacetylase (DLAT) (C-Term) Peptide
DLAT
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975821
Quick Overview for Dihydrolipoyl Transacetylase (DLAT) (C-Term) Peptide (ABIN975821)
Target
DLAT
(Dihydrolipoyl Transacetylase (DLAT))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DLAT antibody (Catalog #: ARP41995_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DLAT (Dihydrolipoyl Transacetylase (DLAT))
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Background
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DLAT is dihydrolipoamide acetyltransferase, the E2 subunit of the mammalian pyruvate dehydrogenase complex of the inner mitochondrial membrane. Patients with primary biliary cirrhosis show autoantibodies to DLAT.The DLAT gene encodes dihydrolipoamide acetyltransferase (EC 2.3.1.12), the E2 subunit of the mammalian pyruvate dehydrogenase complex (PDC, EC 1.2.4.1) of the inner mitochondrial membrane. Patients with primary biliary cirrhosis (PBC, MIM 109720) show autoantibodies to DLAT.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2696 AK057299.1 1-2696 2697-3933 BC039084.1 2066-3302 3934-4322 DB551427.1 98-486
Alias Symbols: DLTA, PDC-E2, PDCE2
Protein Interaction Partner: PDHA1,PDHX,PDK1,PDK2,PDK3,PDK4,PDHB,PDHX,PDK1,PDK2,PDK3
Protein Size: 647 -
Molecular Weight
- 69 kDa
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Gene ID
- 1737
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NCBI Accession
- NM_001931, NP_001922
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UniProt
- Q86YI5
Target
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