DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2) (C-Term) Peptide
DNAJC2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975915
Quick Overview for DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2) (C-Term) Peptide (ABIN975915)
Target
DNAJC2
(DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- EINEQIRKEK EEAEARMRQA SKNTEKSTGG GGNGSKNWSE DDLQLLIKAV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DNAJC2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
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Background
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This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.
Alias Symbols: MPHOSPH11, MPP11, ZRF1, ZUO1
Protein Interaction Partner: HSPA8,HSPA14
Protein Size: 621 -
Molecular Weight
- 72 kDa
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Gene ID
- 27000
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NCBI Accession
- NM_014377, NP_055192
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UniProt
- Q99543
Target
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