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DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2) (C-Term) Peptide

DNAJC2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975915
  • Target See all DNAJC2 products
    DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    EINEQIRKEK EEAEARMRQA SKNTEKSTGG GGNGSKNWSE DDLQLLIKAV
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-DNAJC2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
    Background
    This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.

    Alias Symbols: MPHOSPH11, MPP11, ZRF1, ZUO1

    Protein Interaction Partner: HSPA8,HSPA14

    Protein Size: 621
    Molecular Weight
    72 kDa
    Gene ID
    27000
    NCBI Accession
    NM_014377, NP_055192
    UniProt
    Q99543
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