Double C2-Like Domains, alpha (DOC2A) (N-Term) Peptide
Quick Overview for Double C2-Like Domains, alpha (DOC2A) (N-Term) Peptide (ABIN975942)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- HCSILRAKGL KPMDFNGLAD PYVKLHLLPG ACKANKLKTK TQRNTLNPVW
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DOC2A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DOC2A (Double C2-Like Domains, alpha (DOC2A))
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Background
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There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes, these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release.
Alias Symbols: Doc2
Protein Interaction Partner: DYNLT1,STXBP1,UNC13B,UNC13B
Protein Size: 400 -
Molecular Weight
- 44 kDa
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Gene ID
- 8448
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NCBI Accession
- NM_003586, NP_003577
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UniProt
- Q14183
Target
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