Diphthamide Biosynthesis Protein 2 (DPH2) Peptide
DPH2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975968
Quick Overview for Diphthamide Biosynthesis Protein 2 (DPH2) Peptide (ABIN975968)
Target
DPH2
(Diphthamide Biosynthesis Protein 2 (DPH2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DPH2 antibody (Catalog #: ARP51958_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DPH2 (Diphthamide Biosynthesis Protein 2 (DPH2))
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Background
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This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DPH2L2
Protein Size: 489 -
Molecular Weight
- 52 kDa
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Gene ID
- 1802
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NCBI Accession
- NM_001384, NP_001375
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UniProt
- Q9BQC3
Target
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