Dystrobrevin, beta (DTNB) Peptide
DTNB
Reactivity: Human
Host: Synthetic
BP, WB
Quick Overview for Dystrobrevin, beta (DTNB) Peptide (ABIN976017)
Target
Dystrobrevin beta (DTNB)
(Dystrobrevin, beta (DTNB))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DTNB antibody (Catalog #: ARP46310_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))
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Background
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DTNB is dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin.This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MGC17163, MGC57126
Protein Interaction Partner: BEGAIN,C1orf182,CCDC85B,DMD,DTNB,DTNBP1,HMG20A,KIF5A,NUP62,PPFIBP2,PRTFDC1,SNTG1,SNTG2,TRAF2,UTRN,BEGAIN,C1orf182,CCDC85B,DMD,HMG20A,KIF5A,KIF5B,NUP62,PPFIBP2,PRTFDC1,SNTA1,TRAF2
Protein Size: 567 -
Molecular Weight
- 64 kDa
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Gene ID
- 1838
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NCBI Accession
- NM_033148, NP_149160
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UniProt
- O60941
Target
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