Dyslexia Susceptibility 1 Candidate 1 (DYX1C1) (Middle Region) Peptide
Quick Overview for Dyslexia Susceptibility 1 Candidate 1 (DYX1C1) (Middle Region) Peptide (ABIN976072)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- TDNANARMKA HVRRGTAFCQ LELYVEGLQD YEAALKIDPS NKIVQIDAEK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DYX1C1 Antibody(ARP52548_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))
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Background
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This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.
Alias Symbols: DYX1, DYXC1, EKN1, FLJ37882, MGC70618, RD
Protein Interaction Partner: HSPA1A,STUB1,GABARAP,GABARAPL1
Protein Size: 420 -
Molecular Weight
- 48 kDa
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Gene ID
- 161582
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NCBI Accession
- NM_130810, NP_570722
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UniProt
- Q8WXU2
Target
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