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Dyslexia Susceptibility 1 Candidate 1 (DYX1C1) (Middle Region) Peptide

DYX1C1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN976072

Quick Overview for Dyslexia Susceptibility 1 Candidate 1 (DYX1C1) (Middle Region) Peptide (ABIN976072)

Target

DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))

Origin

Human

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequence

    TDNANARMKA HVRRGTAFCQ LELYVEGLQD YEAALKIDPS NKIVQIDAEK

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-DYX1C1 Antibody(ARP52548_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))

    Background

    This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.

    Alias Symbols: DYX1, DYXC1, EKN1, FLJ37882, MGC70618, RD

    Protein Interaction Partner: HSPA1A,STUB1,GABARAP,GABARAPL1

    Protein Size: 420

    Molecular Weight

    48 kDa

    Gene ID

    161582

    NCBI Accession

    NM_130810, NP_570722

    UniProt

    Q8WXU2
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