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Interleukin-27 subunit beta (IL-27b) (Middle Region) Peptide

IL-27b Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN976103
  • Target See all EBI3 (IL-27b) products
    EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    TAVHPWGSSS SFVPFITEHI IKPDPPEGVR LSPLAERQLQ VQWEPPGSWP
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-EBI3 Antibody(ARP42257_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))
    Target Type
    Viral Protein
    Background
    This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.

    Alias Symbols: IL27B, IL-27B

    Protein Interaction Partner: CANX,GOSR1,IL12A,IL27RA,MDFI,SMAD3,CANX,GOSR1,IL27RA,MDFI

    Protein Size: 229
    Molecular Weight
    23 kDa
    Gene ID
    10148
    NCBI Accession
    NM_005755, NP_005746
    UniProt
    Q14213
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