Ectodysplasin A (EDA) Peptide
EDA
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976121
Quick Overview for Ectodysplasin A (EDA) Peptide (ABIN976121)
Target
Ectodysplasin A (EDA)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-EDA antibody (Catalog #: ARP44518_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Ectodysplasin A (EDA)
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Background
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EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. It belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.
Alias Symbols: ED1, ED1-A1, ED1-A2, EDA1, EDA2, HED, XHED, XLHED, ODT1, STHAGX1
Protein Interaction Partner: EDA,EDA2R,EDAR,FURIN,EDAR
Protein Size: 389 -
Molecular Weight
- 41 kDa
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Gene ID
- 1896
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NCBI Accession
- NM_001005609, NP_001005609
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UniProt
- Q92838
Target
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