Early Growth Response 4 (EGR4) Peptide
EGR4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976190
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Early Growth Response 4 (EGR4) Peptide (ABIN976190)
Target
EGR4
(Early Growth Response 4 (EGR4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-EGR4 antibody (Catalog #: ARP38090_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Early Growth Response 4 (EGR4) peptide
EGR4 Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EGR4 (Early Growth Response 4 (EGR4))
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Background
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The nerve growth factor-induced clone C (NGFI-C/EGR4) gene is a zinc-finger transcription factor that is rapidly induced by nerve growth factor in rat pheochromocytoma PC12 cells and by seizure in brain. NGFI-C/EGR4 is closely related to the previously described early response genes, nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR-4 functionally cooperate with NFAT proteins and induce expression of IL-2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
Alias Symbols: NGFIC, NGFI-C, PAT133
Protein Interaction Partner: NFATC2
Protein Size: 486 -
Molecular Weight
- 51 kDa
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Gene ID
- 1961
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NCBI Accession
- NM_001965, NP_001956
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UniProt
- Q05215
Target
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