Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (N-Term) Peptide
EIF3E
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN976223
Quick Overview for Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (N-Term) Peptide (ABIN976223)
Target
EIF3E
(Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-EIF3E antibody (Catalog #: ARP48175_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
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Background
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EIF3E belongs to the eIF-3 subunit E family.It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. EIF3E is required for nonsense-mediated mRNA decay (NMD), It may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. The protein may interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
Alias Symbols: EIF3-P48, EIF3S6, INT6, eIF3-p46
Protein Interaction Partner: tax,BAT2,COPS6,COPS7A,COPS7B,COPS8,DDX24,EIF3C,EIF3L,EIF4ENIF1,EPAS1,GPAA1,GPBP1L1,HAP1,IFIT1,NDRG1,NSF,RUNDC3A,SMAD9,TRIM27,BAT2,CNTF,COPS6,CSN3,DDX24,EIF1B,EIF3A,EIF3F,EIF3H,EIF3L,GPAA1,GPBP1L1,HAP1,IFIT1,MAGED1,NSF,RGS2,RUNDC3A,SAP18,TRIM27,USP20
Protein Size: 445 -
Molecular Weight
- 52 kDa
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Gene ID
- 3646
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NCBI Accession
- NM_001568, NP_001559
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UniProt
- P60228
Target
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